In a back corner of the University of Missouri’s medical building, a few floors above the hospital and tucked away to the right, Habib Zaghouani watches a cellular war. He has been up there for seven years, with an army of graduate students and a colony of mice, trying to understand why our bodies attack us and how we can make them stop.
Habib Zaghouani, along with his team of graduate and post-doctoral fellows, is working on four different projects in the lab. The first examines why newborn babies are so susceptible to infection, the second tries to understand how the immune system’s memory works, while the third and fourth aim at developing treatments for specific diseases: type I diabetes and multiple sclerosis.
Jason Ellis leads the project that examines how a T cell decides whether to live or die after fighting an infection. These memory T cells, the ones that remain, keep the same illness from happening all over again, and vaccines are based on this same principle.