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At First Sight

A visit with Kristina Narfström, Professor, Department of Veterinary Medicine and Surgery

By Sean Powers
Published: - Topics: vision eyes retina animals testing

Using Gene Transfer to Replace Dead Photoreceptors

Topics: photoreceptor vision

Genetic transfer can be used to replace dead photoreceptor cells. Narfström employs this method to correct protein defects in the eyes. The procedure involves injecting a construct – a vehicle that brings the protein the correct DNA – into the retina cell. The construct is then transported into the nucleus, where it is translated to make the correct protein.